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Clinical Systems Innovation (CSI)


Clinical healthcare environments are demanding, fast-paced, and complex. The barriers to innovation are significant, including the need to avoid disrupting ongoing day-to-day activities.

CIMIT’s model of developing clinical innovation “learning laboratories” across the continuum of care—from the hospital to the home—provides venues for technology and process innovation to address these challenges in realistic settings. It also provides a controlled environment to measure the impact of change.

The Clinical Systems Innovation (CSI) Program is CIMIT’s on-the-ground initiative to improve and advance the systems that support clinical care in real-world healthcare settings. CIMIT helps clinicians and institutions craft novel approaches to implementing a complex new care pathway or designing a new facility or better process, usually incorporating new technology.

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  • Projects
  • Publications
  • Forum/Events
  • In The News
  • Multimedia
FY 2008 - 2012 Clinical Systems Innovation /
Integrated Clinical Environments Projects
2012 Lee Park, MD Newton-Wellesley Hospital Analyzing hospital readmissions to design interventions
2012 Naren Gupta, MBBS, PhD VA Boston Healthcare System An integrated clinical system to reduce stroke risk in patients with carotid disease
2012 Trudy Pang Beth Israel Deaconess Medical Center Development of a Stat EEG Prototype for Rapid Diagnosis of Non-convulsive Status Epilepticus for Community Hospital Settings
2012 Steven Horng Beth Israel Deaconess Medical Center Developing and Validating an Integrated Intelligent Sepsis Monitoring System
2012 L. Michael Fraai Brigham and Women’s Hospital Hospital Readmission Reduction Pilot
2012 Elissa Weitzman Children's Hospital Boston Improving Healthcare Transitions Using a Personally Controlled Health Record
2012 David Hooper Massachusetts General Hospital Integrating Clinical Systems to Identify MRSA-Colonized Patients in the Outpatient Setting with Rapid Detection Methods
2012 Wilton Levine Massachusetts General Hospital Blood Ordering and Transfusion Safety System
2012 Mark Ottensmeyer Massachusetts General Hospital Low Cost, Modular Enhancements for Mannequin-Based Medical Simulators
2012 Julian Goldman Massachusetts General Hospital Improving Continuity of Care for Veterans by Electronically Exchanging MGH, VA, and DoD Medical Record Data
2012 Timothy Bickmore Northeastern Optimizing Hospital Workflow and Quality through Patient Engagement
2012 Steven Simon VA Boston Healthcare System Interactive Medication Reconciliation by Secure Messaging
2011 Julian Goldman, MD Massachusetts General Hospital PCA Monitoring Safety Interlock to Decrease Adverse Clinical Events
2011 James Gray Beth Israel Deaconess Medical Center Using network analysis to improve the qualities of NICU care teams and their function
2011 David Judge, MD Massachusetts General Hospital Implementation of a Hypertension Remote Monitoring Toolkit in a Primary Care Team-Based Practice, Clinical Systems Innovation
2011 Joel Karlinsky VA Boston Healthcare System Interoperability of Portable X Ray Machines with Ventilators in Monitored Settings
2011 Frank Moss Massachusetts Institute of Technology Collaborative Virtual Rehabilitation Interface with Home Treatment Integration
2011 Joanne Nowak Partners Hospice Telehospice Pilot to Connect Patients at End of Life and their Families to Providers to Reduce Rehospitalization and Control Healthcare Costs
2011 Jussi Saukkonen, MD Boston University Development of an interactive, clinical algorithm-driven interoperable smart ventilator.
2011 Kim Wilson Children's Hospital Boston Using Mobile Electronic Protocols to Improve Newborn Survival in Developing Country Settings
2010 Meghan Dierks, MD Beth Israel Deaconess Medical Center Reshaping systems, processes and controls to optimize outcomes in sepsis
2010 Debra Weiner, MD, PhD Children's Hospital Boston Handheld simulation procedure training device
2009 Ronald Dixon, MD
Massachusetts General Hospital Healthcare 360:  A technology-enabled model for general medical care
2009 Ronald Dixon, MD
Massachusetts General Hospital Primary Care Kiosks: Making Solutions Affordable and Scalable
2009 Ronald Newbower, PhD Massachusetts General Hospital Handwashing Compliance Reminder and Documentation
2008 Walter Dzik, MD
Massachusetts General Hospital RFID for Prevention of Bedside Errors
2008 Julian Goldman, MD
Massachusetts General Hospital Medical Device Mobile Plug-and-Play Platform (MD MP3) for Medication Safety
2008 Robert Insoft, MD
Brigham and Women’s Hospital Improving the Care of Neonates During Inter-hospital Transport
2008 David Judge, MD
Massachusetts General Hospital Designing the Ambulatory Practice of the Future Systems Integration Hub
2008 Bruce Levy, MD Brigham and Women’s Hospital Remotely Monitored Inhaler to Predict and Prevent Asthmas Attacks
2008 Adam Wolfberg, MD, MPH

Children’s Hospital Boston The Safe Fetus Project: Develop a new non-invasive monitor of fetal health
Recent Publications by CIMIT Investigators
Bamberg, S. J. M., Picard, R., Paradiso, J. A. Gait & Posture Pattern Recognition of Normal and Healthy Gait Using a Shoe-Integrated Wireless Sensor System 2007
Bamberg, S. J. M., Benbasat, A. Y., Scarborough, D. M., Krebs, D. E., Paradiso, J. A. IEEE Transactions on Information Technology in Biomedicine Gait Analysis Using a Shoe-Integrated Wireless Sensor System 2007
Carleton PF, Lugn N, et al. R Wootton, S Dimmick, J Kvedar. London: Royal Society of Medicine. Congestive Heart Failure Home Telehealth: Connecting Care Within the Community 2007
Egan MT, Sandberg WS Surg Innov. 14(1):41-50; discussion 51 Auto identification technology and its impact on patient safety in the Operating Room of the Future.  2007
Forde RE, DeBros FM, Guimaraes EL, Sandberg WS Anesthesiology. 107(6):1038-9; discussion 1039-40 Misleading behavior of Masimo pulse oximeter tone during profound bradycardia.  2007
Seim AR, Dahl DM, Sandberg WS J Endourol. 21(7):703-8 Small changes in operative time can yield discrete increases in operating room throughput.  2007
Sokal SM, Chang Y, Craft DL, Sandberg WS, Dunn PF, Berger DL Arch Surg. 142(4):365-70 Surgeon profiling: a key to optimum operating room use.  2007
Stahl JE, Goldman JM, Rattner DW, Gazelle GS  J Surg Res 139(1):61-7 Adapting to a new system of surgical technologies and perioperative processes among clinicians.  2007
Clinical Systems Innovation at the
CIMIT Forum and Past Events

Feb. 16, 2010
Susan Edman-Levitan, PA:
Executive Director, The John D. Stoeckle Center for Primary Care Innovation, Massachusetts General Hospital
Designing Solutions Through the Eyes of the Patient: Avoiding "End-User Failure"

The FDA Center for Devices and Radiological Health (CDRH) Workshop on Medical Device Interoperability

Jan. 25-27, 2010

Charles P. Friedman, PhD., Chief Scientific Officer, Office of the National Coordinator for Health Information Technology

Jeffrey Shuren, MD, JD, Acting Director, FDA/CDRH

Donna-Bea Tillman, PhD, Director, Office of Device Evaluation, FDA/CDRH

Doug Rosendale, D.O. F.A.C.O.S, Veterans Health Administration, Office of Health Information, Joint Interoperability Ventures

The Food and Drug Administration (FDA) Center for Devices and Radiological Health, in co-sponsorship with Continua Health Alliance and the Center for Integration of Medicine & Innovative Technology (CIMIT) held a public workshop entitled ‘‘Medical Device Interoperability: achieving safety and effectiveness.’’ The purpose of the workshop is to facilitate discussion among FDA, industry, academia, professional societies, clinical investigators and other interested parties on issues related to safe and effective interoperable medical devices. 

Final Agenda & Videos.


Dec. 8, 2009

Jaques Reifman, PhD: Senior Research Scientist, DoD Biotechnology High-Performance Computing Software Applications Institute, TATRC, U.S. AMRMC, Ft. Detrick, Maryland

Collin M. Stultz, MD, PhD: Principal Investigator, Research Laboratory of Electronics and W. M. Keck Associate Professor of Biomedical Engineering, MIT

• Predictive Models for Individualized Medicine: Tools to Manage Cognitive Performance, Diabetes, and Heat Stress

• A Novel Non-invasive ECG-based Method for Predicting Adverse Cardiovascular Outcomes


Sep. 15, 2009

Lamont M. Yoder, RN, MSN, MBA, NEA-BC, FACHE: Vice President & Chief Nursing Officer, OhioHealth, Inc., Dublin Methodist Hospital

Barbara Blakeney, RN MS: MGH

Julian Goldman, MD: Partners HealthCare

Ronald Newbower, PhD: CIMIT

Sue Schade: BWH

• Transformation via Technology: Run Until Apprehended

• Panel Discussion

Forum: "Living Laboratories" Across the Continuum of Care: Innovative Spaces and Virtual Places  

May 26, 2009

Ronald Newbower, PhD: CTO and Strategic Director, CIMIT Operating Room of the Future

Colleen Kigin, DPT, FAPTA: Chief of Staff, Government Affairs Liaison and Consortium, National, and International Relations, CIMIT

Clare Tempany, MB BAO, BCH: Ferenc Jolesz Distinguished Chair in Radiology Research; Vice Chairman, Radiology Research; Director, Clinical Focused Ultrasound, Department of Radiology, BWH; Professor of Radiology, HMS

David Judge, MD: Co-Program Leader, CSI, Ambulatory Practice of the Future, CIMIT; Instructor in Medicine, HMS; Assistant Medical Director, Bulfinch Medical Group, MGH

Ronald Dixon, MD, MA: Associate Medical Director, MGH Beacon Hill Internal Medicine Associates; Director, Virtual Practice Project, MGH

• Introduction

• Operating Room of the Future

• Advanced Procedure Room

• Ambulatory Practice of the Future

• Virtual Primary Care


May 12, 2009

Julian Goldman, MD, Medical Director of Biomedical Engineering, Partners HealthCare; Principal Anesthesiologist, MGH "Operating Room of the Future"; CIMIT Director of Interoperability; Founder, Medical Device "Plug-and-Play" Interoperability Program

Andrew Reisner, MD, Emergency Physician, MGH; HMS, MIT, and US Army Telemedicine and Advanced Technology Research Center

Peter Szolovits, PhD, Professor of Computer Science and Engineering, MIT Department of Electrical Engineering and Computer Science; Professor of Health Sciences and Technology, Harvard/MIT Division of Health Sciences and Technology; Head, Clinical Decision-Making Group, MIT Computer Science and Artificial Intelligence Laboratory

• Improving Patient Safety and Clinical Workflow: System Integration through Medical Device Interoperability

• Panel Discussion
Forum: Health 2.0: Connecting, Enabling Healthy Behaviors and Taking Charge of Health Records

Jan. 20, 2009

Kenneth Mandl, MD, MPH: Associate Professor, CHB / HMS, Harvard-MIT Health Sciences and Technology

John Moore, MD: Research Assistant, New Media Medicine Group, MIT Media Lab

Jay Parkinson, MD, MPH: Myca

• Personally Controlled Health Records: Tectonic Shifts in the Health Information Economy

• Persuasive Interfaces for Medicine: Enabling Patients to Change Health-related Behaviors

• Hello Health: A Social Network for Clinicians to Communicate with Patients and Clinicians


Dec. 2, 2008
Keith McCandless: Social Invention Group

Ronald Dixon, MD, MA: Associate Medical Director, MGH Beacon Hill Internal Medicine Associates; Director, Virtual Practice Project, Massachusetts General Hospital

• Unleashing Innovation on the Front Lines—Preventing MRSA Transmissions & Transforming Culture

• Innovation “Now" in the Clinical Office Practice

Forum: Retail-based Healthcare Clinics

Sept. 9, 2008

Peter Markell, Vice President, Finance, Partners HealthCare System, Inc.

Ahmed Albaiti, CEO, Medullan, Inc.

• Retail Clinics -The View from an Academic Integrated Delivery System

• Increasing Health Care Value via Technology: Enabled Simplification


Jun. 24, 2008

Jeanine Wiener-Kronish, MD, MGH

Douglas Raines, MD, MGH

Emery Brown, MD, PhD, MGH

Keith Miller, DPhil, MGH

Developments for the Future of Anesthesia and Critical Care
Forum: Planning for the Neonatal Intensive Care Unit

Nov. 27, 2007
Stella Kourembanas, MD; CHB, HMS

Anne Hansen, MD, MPH; CHB, HMS

Jonathan Kemp, PhD; Cambridge Sound Mgmt
Technology Requirements in the NICU of the Future: A First Look at Sight and Sound

• NICU of the Future Project, CHB: Current Challenges and Future Goals

• NICU of the Future, Sound and Light

• Noise in the Clinical Environment: Sources, Effects, Solutions
Forum: Assessing Health of Older Adults

Nov. 6, 2007
Alan M. Jette, PT, PhD, FAPTA; BU, BUMC

Jonathan Bean, MD, MS, MPH; Spaulding Cambridge Outpatient Center, HMS   
• How Are You Really Doing? Innovations in Functional Outcomes Measurement in Rehabilitation

• Three Big Risks for Older Adults: Walking, Climbing Stairs and Rising from a Chair: Evidence-based Rehabilitative Care for Older Adults
Forum: Improving Quality and Patient Safety

Oct. 30, 2007
Ronald Newbower, PhD; CIMIT

Gregg S. Meyer, MD, MSc; MGH/MGPO

Jeffrey Cooper, PhD; MGH    
• How to Protect Oneself From Injury by Human Error in a Hospital

• An Untapped Role for Patients: Online Reconciliation of Meds and Monitoring Care Transitions

• New Hazards of Medical Technology
Forum: Challenges and Opportunities in Office-Based Medicine

Oct. 9, 2007
Keith Isaacson, MD; HMS, BWH, BWH

Fred Shapiro, DO; HMS, BIDMC

Beverly Philip, MD; HMS, BWH

Lisa Warren, MD; MGH

• Office-based Gynecologic Procedures

• Office-based Anesthesia 

• Technology Implications of Office-based Anesthesia Safety

• Regional Anesthesia in the Office Based Setting

Clinical System Innovation News
iPhone Apps for the Clinic Gosh, that's neat! Blog Feb. 16, 2010
Oct. 9, 2009
Healthcare IT News Oct. 6, 2009
Five emerging sectors offer promise with new technologies Mass High Tech Jul. 31, 2009
Dr. Ronald Dixon Featured 'Healthcare Revolution' Expert:

VIDEO: Making Primary Care The Primary Focus

VIDEO: Fulfilling Healthcare’s Digital Promise

VIDEO: Downloading Health: Why Don’t Doctors Use Text Messaging and Email?

VIDEO: Tough Medicine: A Big Think Interview With Ron Dixon About Reinventing Healthcare Jul. 16, 2009
$150,000 Engineering Prize awarded to CollaboRhythm Team.
CIMIT Prize competition recognizes student research using novel technologies to address major diagnostic and therapeutic challenges in primary healthcare.
CIMIT Press Release Jun. 25, 2009
Boston Globe Jun. 1, 2009
The Doctor Kiosk. An automated health-care interface aims to streamline preventative screening Technology Review Feb. 25, 2009
Health data kiosk replaces in-person doctor visits Mass High Tech Feb. 6, 2009
Medical devices lag in iPod age. Patients' safety is at risk, experts say Boston Globe Dec. 29, 2008
Model Contract Gives Momentum To Interoperability Movement
Anesthesiology News Dec. 2008
"Plug and Play" Hospitals, Medical devices that exchange data could make hospitals safer. MIT Tech Review July 9, 2008
Doc: Plug-and-play med devices could save lives Mass High Tech Jan. 18, 2008
Scientific and Educational Exhibit: First-place tie winners from Massachusetts General Hospital/Harvard Medical School American Society of Anesthesiologists Jan. 8, 2008
How to Improve It?
Ask Those Who Use It
New York Times Mar. 25, 2007
Personalized Medical Monitors: John Guttag says using computers to automate some diagnostics could make medicine more personal
Technology Review Mar. 12, 2007
ASA Panel on Medical Device Interoperability Anesthesiology News Feb. 1, 2007
Once a Tech Fantasy, Plug-and-Play OR Edges Closer to Reality Anesthesiology News Jan. 2007
OR of Future Reports Improved Throughput OR Manager Jan. 2006
BWH Achieves World First in Thoracic Surgery BWH Pike Notes Dev. 9, 2005
Automatic Detection and Notification of 'Wrong Patient-Wrong Location' Errors in the Operating Room Surgical Innovation Sept. 2005

Program Leader

Penny Ford Carleton, RNPenny Ford Carleton,


Program Leader,
Clinical Systems Innovation


Janssen at Johnson & Johnson 2012 Connected Care Challenge: Submission Deadline March 25
Providing awards totaling $250,000 to entrepreneurs with the best solutions for improving patient transitions from hospital to home

$10 Million NIH Quantum Grant Awarded to Interoperability Team
Led by Dr. Julian Goldman
Program designed to make quantum improvements in health

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Related Links

Connected Health
Partners Home Care
Medical Device Plug-and-Play

Shaping the Future of Healthcare

"Connected Care" Interactive Graphic.

CSI Program Alliance

European Connected Health Campus


Integrated Clinical EnvironmentsNeuroHealth, PTSD & TBI Industry I Foundation Engagement Homebase & Warfighter CareAccelerator

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