The Future of Neurotechnology

4:00PM  The Neurotechnology Industry: 2008 and Beyond
Zack Lynch
, Executive Director, Neurotechnology Industry Organization
Moderator: Warren B. Lammert
, Co-founder and Director, The Epilepsy Therapy Project and epilepsy.com; Principal and Chief Investment Officer, Granite Point Capital

Two billion people worldwide are afflicted with neurological problems ranging from addiction to epilepsy.  The annual economic burden caused by these conditions is estimated to be $1.1 trillion in the United States alone.  The growing neurotechnology industry generated around $130 billion in global revenue in 2007, and it currently produces a wide range of products including drugs, devices, and diagnostics.  Most of the industry’s revenue comes from selling pharmaceuticals, but companies producing devices and diagnostic tools appear poised for strong growth.  The number of neurotechnology patents being filed each year is going up, and the number of deals between companies is also increasing.  Although a neurotechnology tracking index created in 2007 has not performed very well, the industry has attracted billions of dollars in funding from venture capitalists, and exciting developments are on the horizon. 

      

The Neurotechnology Industry Organization (NIO) is a recently formed trade association seeking to give the neurotechnology industry a collective voice.  The NIO has pushed the federal government to pass the National Neurotechnology Initiative Act, a bill providing $200 million for research coordination, for analyses of the social implications of neurotechnology, and for efforts to make the product review process more efficient.

 

In the future, neurotechnology may become a very important part of human society.  It could even launch a technological revolution in which artificial brain enhancement might become common.  Today, pills exist to improve one’s powers of concentration, and it is not inconceivable that drugs could soon be created to boost memory and improve learning.  Perhaps people will also seek to manipulate their emotions.  Although the ethics of mental enhancement are controversial, global competition might cause refusing to participate in this practice to become unaffordable.  Neurotechnology holds much promise, but it could also pose serious dangers if it is misused.     

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5:00PM  Towards Model Based Control of Epileptic Seizures
Steven Schiff
, MD, PhD, Director, Pen State Center for Neural Engineering; Brush Chair Professor of Engineering; Professor of Neurosurgery, Professor of Engineering Science and Mechanics, Professor of Physics
Moderator: Steven Schachter, MD, Professor Neurology, Harvard Medical School; Neurotechnology Program Leader, CIMIT; Department of Neurology, Beth Israel Deaconess Medical Center

There is a long history of electrical stimulation to treat epileptic seizures, but none of it has been able to utilize the effective forms of modern control engineering. This situation is about to change. It is based upon the convergence of increasing understanding of the mechanisms of seizures, computational models that reflect such mechanisms, and the advances in model based control that now permit us to incorporate the features in neuronal models that previously prevented such applications. Such techniques are not restricted to epileptic seizures, but are also applicable to the control of cognitive rhythms, and the modulation of motor system dysfunction as in Parkinson¹s disease.

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